Translational PsychiatryApril 21, 2026Paul A Parcon, Amanda Bardhoshi, Amanda Olsen-Dufour et al.
The N-methyl-D-aspartate (NMDA) receptor antagonist ketamine is a robust, rapid-acting antidepressant whose molecular effects have not been fully elucidated. Phosphodiesterase-4 (PDE4), which terminates cyclic adenosine monophosphate (cAMP) activity, may underlie antidepressant response. In particular, previous studies found that whole brain binding of the positron emission tomography (PET)...
InTech eBooksSeptember 6, 2017Shawn Wu, Lin Hua Jiang, J. Wang
Recently, much more mind-body/mindfulness interventions have been used in different people including frail elders, patients with major depressive order, pain suffering, chronic fatigue, infection, and patients in intensive care unit, etc. In the field of Complementary and Alternative Medicine, many Chinese mind-body exercises are under very active investigation for evidence-based decision...