Tsung-Ta Liu

2 papers in the library · publishing 2016-2023

Papers

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Therapeutic effects of methimazole on 3,4-methylenedioxymethamphetamine-induced hyperthermia and serotonergic neurotoxicity.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie August 1, 2023 I-Hsun Li, Tsung-Ta Liu, Ying-Chen Chen et al.

3,4-methylenedioxymethamphetamine (MDMA) is a popular recreational drug, however over 200 studies demonstrate that acute (e.g. hyperthermia, rhabdomyolysis) and chronic (e.g. neurotoxicity) toxicity effects of MDMA were observed in different animals. Methimazole (MMI), an inhibitor of thyroid hormone synthesis, was found to significantly reduce the HSP72 expression of heat stress induced in...

DOI: 10.1016/j.biopha.2023.114880 Full text MDMA Forced swimming test Hyperthermia Methimazole +2

Effects of dextromethorphan on MDMA-induced serotonergic aberration in the brains of non-human primates using [123I]-ADAM/SPECT.

Scientific Reports December 12, 2016 Kuo-Hsing Ma, Tsung-Ta Liu, Shao-Ju Weng et al.

3,4-Methylenedioxymethamphetamine (MDMA), a common recreational drug, is known to cause serotonergic neurotoxicity in the brain. Dextromethorphan (DM) is a widely used antitussive reported to exert anti-inflammatory effect in vivo. In this study, we examined the long-term effect of MDMA on the primate serotonergic system and the protective property of DM against MDMA-induced serotonergic...

DOI: 10.1038/srep38695 Full text Serotonin Brain Animals Primates +7