MDMA-Assisted Therapy for Social Anxiety Disorder: A Randomized, Open-label, Wait-list Controlled Trial
June 4, 2026 Jason B. Luoma, M. Kati Lear, Brian Pilecki et al. preprint
Background: ±3,4-methylenedioxymethamphetamine (MDMA) has positive effects on socio-emotional processing and MDMA-Assisted Therapy (MDMA-AT) showed promise for treating SAD in a previous placebo-controlled trial. Aims: Develop a preliminary estimate of clinical response and safety for MDMA-AT versus waitlist in adults with SAD. Secondary aims included refinement of a standardized psychotherapy...
DOI: 10.31234/osf.io/a9x6d_v1 (opens in new tab)
Social anxiety
Randomized controlled trial
Adverse effect
Clinical trial
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