The Role of the Basolateral and Central Amygdala During Heroin Withdrawal and 3,4-Methylenedioxymethamphetamine Administration
UNC Libraries June 5, 2026 Charlotte Rubin
Opioid use disorder (OUD) is characterized by dependence, withdrawal, and high relapse risk, yet the neuroimmune mechanisms underlying withdrawal in the amygdala remain poorly understood. This study investigated whether 3,4-methylenedioxymethamphetamine (MDMA) modulates heroin withdrawal–induced neuroinflammation in the central amygdala (CeA) and basolateral amygdala (BLA). Adult male...