Ketamine for acute management of refractory stiff person syndrome: a case report.
BMC Neurology April 9, 2025 Evan Eggiman, William Kerr, Brandon Spivey et al.
Stiff Person Syndrome (SPS) is a rare autoimmune neurological disorder characterized by progressive muscle rigidity and painful spasms. Standard treatments often yield variable responses, particularly in severe, refractory cases. This case report highlights the novel use of ketamine as an effective therapeutic agent for managing acute SPS exacerbations, underscoring its potential as a...