Evaluation of Neurotoxicity of NBOH Derivatives
Pharmaceuticals July 8, 2026 Rodrigo Foss da Silva, Lennon Machado Alves, Fernanda Conte et al.
Background/Objectives: The study sought to investigate the neurotoxicity of NBOHs, which are a class of new psychoactive substances (NPSs) that act as agonists of serotonin 5-HT2A and 5-HT2C receptors, resulting in hallucinogenic effects similar to those of LSD, often found in paper blotters. Methods: Differentiated SH-SY5Y cells were incubated for 24 h with 0.5, 1.0, 3.5, 5 and 10 nM of the...