Psilocybin restores behavioral and neuroplastic deficits induced by chronic stress in rats.
Progress in neuro-psychopharmacology & biological psychiatry June 20, 2026 Agnieszka Bysiek, Izabela Szpręgiel, Adam Wojtas et al.
Psychedelics have emerged as a promising novel therapeutic approach for major depressive disorder (MDD). Altered activity and structural atrophy of the prefrontal cortex, hippocampus, and limbic structures are associated with depressive disorders. Psilocybin may reverse the loss of synaptic connections and restore the function of these brain regions. In this study, we investigated the effects...