Ketamine for unipolar depression: A systematic review of efficacy and safety.
Australasian Psychiatry June 1, 2025 Tharshanan Edwin Peiris, Amrit Pokhrel, Yuvaraj Paudel 2 citations
BackgroundUnipolar depression is a prevalent mental health disorder with persistent, treatment-resistant symptoms. Traditional antidepressants take weeks to show effects, underscoring the need for faster alternatives. Ketamine, originally an anaesthetic, has emerged as a rapid-acting antidepressant.ObjectiveThis systematic review evaluates ketamine's efficacy and safety in unipolar...
DOI: 10.1177/10398562251328805 (opens in new tab)
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Treatment-resistant depression
Efficacy
Rapid-acting antidepressant
Safety
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