Antidepressants Normalize the Default Mode Network in Patients With Dysthymia
JAMA Psychiatry February 6, 2013 Jonathan Posner, David J Hellerstein, Inbal Gat et al. 275 citations
IMPORTANCE: The default mode network (DMN) is a collection of brain regions that reliably deactivate during goal-directed behaviors and is more active during a baseline, or so-called resting, condition. Coherence of neural activity, or functional connectivity, within the brain's DMN is increased in major depressive disorder relative to healthy control (HC) subjects; however, whether similar...