Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder
JAMA Psychiatry April 16, 2014 Adriana Feder, Michael K. Parides, James W. Murrough et al. 618 citations
IMPORTANCE: Few pharmacotherapies have demonstrated sufficient efficacy in the treatment of posttraumatic stress disorder (PTSD), a chronic and disabling condition. OBJECTIVE: To test the efficacy and safety of a single intravenous subanesthetic dose of ketamine for the treatment of PTSD and associated depressive symptoms in patients with chronic PTSD. DESIGN, SETTING, AND PARTICIPANTS:...