Effectiveness of ketamine/esketamine in alleviating postoperative fatigue: a systematic review
International Journal of Clinical Pharmacy November 12, 2025 Qijing Liu, Ying Liu, Qian Fu et al. 2 citations
Current evidence suggests that ketamine/esketamine may be effective in alleviating POF, particularly in major abdominal surgeries. These findings should be interpreted cautiously due to the heterogeneity in study designs, variations in fatigue assessment tools and time, and the limited sample sizes of the included studies. Future high-quality RCTs are needed to confirm these observations and...