The collective lie in ketamine therapy: a call to realign clinical practice with neurobiology
Frontiers in Psychiatry September 22, 2025 Charles Miller, Bárbara Lopes, Anna Mccurdy
In recent years, ketamine therapy has become increasingly entangled with psychedelic culture, leading to widespread misinterpretation of its therapeutic mechanism. This manuscript challenges the prevailing narrative that positions ketamine as a consciousness-expanding agent or psychotherapy enhancer, highlighting the discord between this view and ketamine's well-established neurobiological...