Jianliang Sun

2 papers in the library · 57 citations · publishing 2024-2025

Papers

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Effects of Continuous Perioperative Esketamine Infusion on Postoperative Depression in Breast Cancer Patients: A Randomized Controlled Double-Blind Trial.

Drug Design, Development and Therapy October 29, 2025 Mengting Shen, Ye Xuan, Kaiyu Chen et al.

Background: Comorbid depressive symptoms are prevalent in patients with breast cancer, which adversely impacts postoperative recovery outcomes. Esketamine has emerged as a promising intervention for perioperative depression due to its rapid and sustained effects. This study aims to investigate the impact of the continuous intravenous infusion of esketamine during the perioperative period on...

DOI: 10.2147/dddt.s540781 Full text Esketamine Humans Breast neoplasms Antidepressive agents +12

Esketamine Prevents Postoperative Emotional and Cognitive Dysfunction by Suppressing Microglial M1 Polarization and Regulating the BDNF-TrkB Pathway in Ageing Rats with Preoperative Sleep Disturbance

Molecular Neurobiology January 15, 2024 Yuxin Wen, Jiawen Xu, Jiahong Shen et al. 57 citations

Postoperative depression (POD) and postoperative cognitive dysfunction (POCD) have placed heavy burden on patients’ physical and mental health in recent years. Sleep disturbance before surgery is a common phenomenon that has been increasingly believed to affect patients’ recovery, especially in aged patients, while little attention has been paid to sleep disruption before surgery and the...

DOI: 10.1007/s12035-023-03860-4 Full text