The Axis Mundi Hypothesis: Endogenous N,N-Dimethyltryptamine as a Neurobiological Bridge Between Conscious and Subconscious Processing - An Integrative Theoretical Framework
Zenodo (CERN European Organization for Nuclear Research) February 12, 2026 Mihai Alexandru
Multiple lines of neuroscientific evidence have converged on a set of closely related findings: the mammalian brain endogenously synthesizes N,N-dimethyltryptamine (DMT) at neurotransmitter-comparable concentrations (Dean et al., 2019); psychedelic compounds suppress the default mode network (DMN) and dissolve ego boundaries (Carhart-Harris et al., 2012; Tagliazucchi et al., 2016); the brain...