Neurochemical characterization of 5-HT 2A R partial agonists with simultaneous PET-MRI
Journal of Cerebral Blood Flow & Metabolism November 29, 2024 Frederick A. Bagdasarian, Kristian Larsen, Deng Hong et al. 1 citation
Understanding neuromodulatory effects of serotonin 2A receptor (5-HT 2A R) agonists with diverse pharmacological profiles is relevant to advancing psychedelic-related drug applications. We performed simultaneous positron emission tomography (PET) and pharmacological magnetic resonance imaging (phMRI) in anesthetized nonhuman primates (NHP; N = 3) to examine partial agonists with varying 5-HT 2A...