In the originally published version of this article, Figure 4 contained an error in the RNA-seq analysis. During data processing, the subtraction order for the treatment groups was inadvertently reversed (vehicle was subtracted from psilocybin-treated samples, instead of psilocybin-treated from vehicle). This error affected the plotted log fold-change values but does not alter the...
Abstract Psilocybin and other serotonergic psychedelics have re-emerged as therapeutics for neuropsychiatric disorders, including addiction. Psilocybin induces long-lasting effects on behavior, likely due to its profound ability to alter consciousness and augment neural connectivity and plasticity. Impaired synaptic plasticity in obesity contributes to ‘addictive-like’ behaviors, including...