Convergent effects of different anesthetics on changes in phase alignment of cortical oscillations.
Cell Reports May 27, 2025 Alexandra G Bardon, Jesus J Ballesteros, Scott L Brincat et al. 8 citations
Many anesthetics cause loss of consciousness despite having diverse underlying molecular and circuit actions. To explore the convergent effects of these drugs, we examine how anesthetic doses of ketamine and dexmedetomidine affect bilateral oscillations in the prefrontal cortex of nonhuman primates. Both anesthetics increase phase locking in the ventrolateral and dorsolateral prefrontal cortex,...