Acute 3,4-Methylenedioxymethamphetamine (MDMA) Toxicity Leading to Fulminant Hepatic Failure and Emergency Liver Transplantation
Cureus December 20, 2025 Marcus Vinícius de Aragão Batista, Miguel Barbosa, José Casimiro et al.
Recreational use of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") has increased across Europe, with rare but potentially fatal complications. We report a case of fulminant hepatic failure and multiorgan dysfunction following acute MDMA intoxication in a previously healthy 22-year-old man. One hour after ingestion, he developed seizures, hyperthermia (43 °C), and cardiovascular collapse....