Effects of ketamine on fear memory extinction: a review of preclinical literature.
Frontiers in Neuroscience 2025 Martin Boese, Rina Y. Berman, Kennett D. Radford et al. 5 citations
Ketamine, a multimodal dissociative anesthetic, is widely used as a trauma analgesic in emergency situations. Ketamine is also used to treat psychiatric disorders due to its broad application potential, including treatment-resistant major depression. However, its impacts on the development of post-traumatic stress disorder (PTSD) and its potential as a treatment for PTSD are controversial. PTSD...
DOI: 10.3389/fnins.2025.1546460 (opens in new tab)
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Fear memory
Molecular mechanism
Translational research
PTSD Treatment
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