Pharmacokinetics and brain distribution of ketamine after nasal administration.
Journal of Pharmaceutical and Biomedical Analysis October 15, 2025 Zihe Yang, Linjie Li, Bin Deng et al. 3 citations
Major depressive disorder is a severe mental condition characterized by abnormalities in the structure and function of the brain. Ketamine is a novel antidepressant that has rapid effects on depression. This drug is clinically used to treat depression in patients with acute suicidal ideation or behavior. It is typically administered at a dose of 84 mg. However, the distribution of ketamine in...
DOI: 10.1016/j.jpba.2025.116945 (opens in new tab)
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Brain region distribution
Hplc-ms/ms
Intranasal administration
Pharmacokinetics
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