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Edward W. Voss

1 paper in the library · 8 citations · publishing 1974

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Mechanism of lysergic acid diethylamide interference with rabbit antibody biosynthesis

Proceedings of the National Academy of Sciences of the United States of America 1974 Edward W. Voss, Jeffrey L. Winkelhake 8 citations

Lymphoid cells from hyperimmune rabbits producing antibodies to a hapten, incubated in the presence of d-lysergic acid diethylamide, continued to synthesize protein at a normal rate. Isoelectric focusing analysis of the low-molecular-weight protein secreted by the cells incubated with lysergic acid diethylamide indicated two components, with pI's of 4.9 and 5.2. Immune cells not exposed to...