Ethanol increases the distribution of MDMA to the rat brain: possible implications in the ethanol-induced potentiation of the psychostimulant effects of MDMA
The International Journal of Neuropsychopharmacology December 2, 2008 Sami Ben Hamida, Antoine Tracqui, Anne Pereira De Vasconcelos et al. 27 citations
Ecstasy (3,4-methylenedioxymethylamphetamine; MDMA) is a popular club drug often taken with ethanol (EtOH). We recently found EtOH potentiated the psychomotor effects of MDMA in rats. This potentiation could reflect pharmacodynamic or/and pharmacokinetic processes. To test the latter hypothesis, rats were injected i.p. with 6.6 or 10 mg/kg MDMA with or without 1.5 g/kg EtOH, and were killed at...
DOI: 10.1017/s1461145708009693 (opens in new tab)
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MDMA
Ecstasy
Pharmacology
Microdialysis
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