Generalizability of Risk Models for Treatment-Resistant Depression Across Three Health Systems.
medRxiv : the preprint server for health sciences May 27, 2025 Colin G Walsh, Michael Ripperger, Thomas H McCoy et al. preprint
As multiple strategies have emerged for managing treatment-resistant major depressive disorder, efficient identification of individuals at elevated risk for this outcome earlier in their illness course remains essential. We extracted electronic health records data for all individuals with a diagnosis of major depressive disorder who received an index antidepressant prescription in the clinical...