Reducedin vivobinding to the serotonin transporter in the cerebral cortex of MDMA (‘ecstasy’) users
The British Journal of Psychiatry July 1, 1999 David Semple, Klaus P. Ebmeier, Michael F. Glabus et al. 281 citations
Background The use of MDMA (‘ecstasy’) is common among young people in Western countries. Animal models of MDMA toxicity suggest a loss of serotonergic neurons, and potentially implicate it in the development of significant psychiatric morbidity in humans. Aims To test whether long-term use of MDMA can produce abnormalities in cerebral serotonin, but not dopamine, transporter binding measured...