5-MeO-DMT Use in Humans: A Scoping Review of Peer-Reviewed Research
January 8, 2026 Michael Esposito, Ana M Ortiz Bernal, Alan K. Davis et al. preprint
Clinical trials using 5-MeO-DMT to treat various mental health conditions are currently underway, however research on 5-MeO-DMT use in humans is limited. To date, no scoping review of the published, peer-reviewed literature exists. The purpose of the present analysis is to examine the extent, range, and nature of peer-reviewed research on the use of 5-MeO-DMT in humans and, ultimately, to...