Biological embedding of early trauma: the role of higher prefrontal synaptic strength
European Journal of Psychotraumatology August 29, 2023 Lihong Jiang, Amanda J. F. Tamman, Christopher L. Averill et al. 8 citations
Background: Early trauma predicts poor psychological and physical health. Glutamatergic synaptic processes offer one avenue for understanding this relationship, given glutamate's abundance and involvement in reward and stress sensitivity, emotion, and learning. Trauma-induced glutamatergic excitotoxicity may alter neuroplasticity and approach/avoidance tendencies, increasing risk for...