Liquid Chromatography-Electrospray Ionization Mass Spectrometry for the Detection of Lysergide and a Major Metabolite, 2-Oxo-3-Hydroxy-LSD, in Urine and Blood
Journal of Analytical Toxicology October 1, 2000 Jason H Sklerov, Joseph Magluilo, K. K. Shannon et al. 30 citations
A method is presented for the quantitative measurement of lysergide (LSD) and its metabolite 2-oxo-3-hydroxy-LSD (O-H-LSD) in urine and blood. O-H-LSD has been reported to have urinary concentrations many times higher than LSD. Measuring its presence in urine would significantly extend the detection time for confirming LSD abuse. A single-step liquid-liquid extraction was performed on 5-mL...