Off-target activity of NBOMes and NBOMe analogs at the µ opioid receptor.
Archives of Toxicology May 1, 2023 Marie H Deventer, Mattias Persson, Antonio Laus et al. 7 citations
New psychoactive substances (NPS) are introduced on the illicit drug market at a rapid pace. Their molecular targets are often inadequately elucidated, which contributes to the delayed characterization of their pharmacological effects. Inspired by earlier findings, this study set out to investigate the µ opioid receptor (MOR) activation potential of a large set of psychedelics, substances which...
DOI: 10.1007/s00204-023-03465-9 (opens in new tab)
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Bioassay
Molecular docking
Nbome
Off-target
+2