Off-target activity of NBOMes and NBOMe analogs at the µ opioid receptor.
Archives of Toxicology May 1, 2023 Marie H Deventer, Mattias Persson, Antonio Laus et al. 7 citations
New psychoactive substances (NPS) are introduced on the illicit drug market at a rapid pace. Their molecular targets are often inadequately elucidated, which contributes to the delayed characterization of their pharmacological effects. Inspired by earlier findings, this study set out to investigate the µ opioid receptor (MOR) activation potential of a large set of psychedelics, substances which...