Rapid and Sensitive Detection of Psilocybin and Psilocin in Urine by Surface‐Enhanced Raman Spectroscopy
Journal of Raman Spectroscopy May 28, 2026 Wei Lin, Hong Chen, Yuanyuan Li
ABSTRACT Psilocybin, one of the primary active compounds in magic mushrooms, is metabolized into psilocin in the human body. In this study, we employed surface‐enhanced Raman spectroscopy (SERS), leveraging its unique molecular fingerprinting capabilities and high sensitivity, in combination with silver‐coated gold nanoparticles (Au@AgNPs) as the enhancement substrate (enhancement factor ~1.14...