André B Negrão

Brief report: Ketamine-assisted "bridge therapy" for opioid tapering in complex cases.

American Journal on Addictions January 28, 2026 Mariana C De Oliveira, Cláudia C De Araujo Palmeira, André B Negrão et al. 1 citation

Opioid use disorder (OUD) presents major challenges, especially when combined with chronic pain and psychiatric comorbidities. A 25-year-old woman with OUD, chronic pain, and major depressive disorder underwent an 8-week protocol of intravenous ketamine infusions (0.5 mg/kg weekly) as an adjunct to opioid tapering. Methadone dosage was reduced by 50%, with improved pain and craving control,...