Unmixing the Psychedelic Connectome: Brain Network Traits of Psilocybin
November 17, 2025 Krishna Prasad Bhavaraju, Natasha L. Mason, Pablo Mallaroni et al. preprint
Abstract Psilocybin induces profound alterations in consciousness, yet prevailing neural models often describe a monolithic change in brain connectivity that may not fully capture the multifaceted nature of the psychedelic state. To test the hypothesis of a composite neural state, this study applied a robust, data-driven framework, Connectome Independent Component Analysis (connICA) with...