A Complex Impact of Systemically Administered 5-HT2A Receptor Ligands on Conditioned Fear
The International Journal of Neuropsychopharmacology July 5, 2021 Sven Melker Hagsäter, Robert Pettersson, Christopher Pettersson et al. 29 citations
Abstract Background Though drugs binding to serotonergic 5-HT2A receptors have long been claimed to influence human anxiety, it remains unclear if this receptor subtype is best described as anxiety promoting or anxiety dampening. Whereas conditioned fear expressed as freezing in rats is modified by application of 5-HT2A–acting drugs locally into different brain regions, reports on the effect of...