Psilocybin induces sex- and context-specific recruitment of the stress axis
Current Biology December 9, 2025 Sarah G. Cook, Stephanie J. Lee, Emma Ference et al. 3 citations
Following decades of prohibition, psychedelic drugs have reemerged as promising therapeutics for stress-related conditions, including depression and post-traumatic stress disorder. Still, their impact on stress-related brain regions and the hypothalamic-pituitary-adrenal (HPA) axis remains unclear. This work explores the acute effects of psilocybin on the primary regulators of the HPA axis:...