Abstract Psilocybin increases social connectedness and has strong clinical transdiagnostic efficacy for mental illness, making it a candidate treatment to reduce maternal disconnect, anxiety, and blunted affect seen in peripartum mood disorders. However, the efficacy and safety of psilocybin in peripartum mood disorders has not been investigated. We used a social stress model to examine the...
Data files associated with the manuscript titled: Psilocybin during the postpartum period induces long-lasting adverse effects in both mothers and offspring. These files contain the analyses used for each figure of the paper including the supplement. The postpartum stress protocol is included along with all of the raw maternal behavior data. Additional raw data can be found in the manuscript...
Abstract Background Peripartum mood disorders (PMDs) are a major public health concern; they present in 20% of birthing parents and are responsible for 1 in 4 maternal deaths in the United States. The psychedelic antidepressant psilocybin (PSI) increases social connectedness, self-compassion, and has strong clinical transdiagnostic efficacy for mental illness – making it a candidate treatment...