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James A. Kaduk

1 paper in the library · 10 citations · publishing 2021

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Psilocybin: crystal structure solutions enable phase analysis of prior art and recently patented examples

Acta Crystallographica Section C Structural Chemistry December 20, 2021 Alexander M. Sherwood, Robert B. Kargbo, Kristi W. Kaylo et al. 10 citations

Psilocybin {systematic name: 3-[2-(dimethylamino)ethyl]-1 H -indol-4-yl dihydrogen phosphate} is a zwitterionic tryptamine natural product found in numerous species of fungi known for their psychoactive properties. Following its structural elucidation and chemical synthesis in 1959, purified synthetic psilocybin has been evaluated in clinical trials and has shown promise in the treatment of...