Skip to content

James Cooke

2 papers in the library · 9 citations · publishing 2024-2026

Papers

Sort Most recent Most cited

Egostasis: A First-Principles Account of the Neurocomputational Basis of Suffering

April 30, 2026 James Cooke preprint

This paper introduces the concept of egostasis (self-based goal-directed persistence behaviour) and proposes a novel neurophenomenological theory of the experience of suffering, grounded in the framework of active inference. We argue that psychological suffering is a transmodal, aversive state arising from prediction errors being attributed to a self-model. Chronic suffering is proposed to...

UK medical students’ self-reported knowledge and harm assessment of psychedelics and their application in clinical research: a cross-sectional study

BMJ Open March 1, 2024 Charlie Song-Smith, Edward Jacobs, James Rucker et al. 9 citations

Objective To capture UK medical students’ self-reported knowledge and harm assessment of psychedelics and to explore the factors associated with support for changing the legal status of psychedelics to facilitate further clinical research. Design Cross-sectional, anonymous online survey of UK medical students using a non-random sampling method. Setting UK medical schools recognised by the...