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Anjali Tarun

2 papers in the library · 7 citations · publishing 2020

Papers

Altered anterior default mode network dynamics in progressive multiple sclerosis

medRxiv Preprint Server November 26, 2020 Giulia Bommarito, Anjali Tarun, Younes Farouj et al. 7 citations preprint

In people with progressive multiple sclerosis, brain function changes are not well understood, but studying them could reveal more about how the disease works at this stage.

NREM sleep stages specifically alter dynamical integration of large-scale brain networks

iScience December 25, 2020 Anjali Tarun, Danyal Wainstein Andriano, Virginie Sterpenich et al.

During non-rapid eye movement (NREM) sleep, the brain's large-scale functional networks show a surprising pattern: nearly all networks are most active during NREM stage 2, then abruptly lose activity in NREM stage 3. However, despite this high activity in stage 2, the functional connections and mutual dependencies between networks progressively break down as sleep deepens. This means that even though networks attempt to communicate during stage 2, the efficiency of information transfer is low. The findings advance neural models of sleep and consciousness by showing that network integrity, not just activity levels, is crucial for conscious awareness.