(R)-Ketamine reduces alcohol intake and alcohol seeking induced by reconsolidation of alcohol-related memories in female Marchigian Sardinian alcohol-preferring rats.
Psychopharmacology November 15, 2025 Elisabetta Ciccocioppo, Sara Massetti, Marcus W. Meinhardt et al.
Alcohol use disorder (AUD) represents a significant medical challenge, with available therapeutic approaches having limited efficacy. Emerging data suggest that psychedelic compounds could represent an alternative treatment for AUD. Among this class of molecules, ketamine, a dissociative psychedelic, shows promising properties. It reduces alcohol drinking in rodents and in humans it is used to...
DOI: 10.1007/s00213-025-06964-y (opens in new tab)
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R-ketamine
Psychedelics
Dissociative psychedelic
Reducing alcohol intake
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