S100B+ Astrocytes Are Altered in the Mouse Brain Upon Ketamine Challenge: Implications for the Symptoms of Schizophrenia.
Journal of Biochemical and Molecular Toxicology December 1, 2025 Nimmi Varghese, Aadithye Ravikumar Nair, Parayil Sobha Anumol et al.
Schizophrenia is a complex neuropsychiatric disorder characterized by positive, negative and cognitive symptoms. The pathophysiology of schizophrenia is largely unknown, but it is understood that this mental disorder is a manifestation of genetic, environmental and biological factors. Herein, we focus on S100B, a family of calcium binding cytosolic proteins that play a profound role in glial...