Role of hippocampal 5-HT1A receptors on elevated plus maze exploration after a single restraint experience.
Behavioural Brain Research May 1, 1996 S M Netto, F S Guimarães 45 citations
Previous studies have shown that 2 h restraint stress induces deficits in open arm exploration of an elevated plus maze 24 h later. This effect was attenuated by a post-stress systemic injection of the 5-HT non-selective agonist, 5-methoxy-N,N-dimethyltryptamine (5-MeODMT). To verify a possible involvement of hippocampal 5-HT1A receptors in this effect, rats were stereotaxically implanted with...