Alteration in Electroencephalogram and Monoamine Concentrations in Rat Brain following Ibogaine Treatment.
Annals of the New York Academy of Sciences May 1, 1998 Zbigniew Binienda, Michael A Beaudoin, Brett T Thorn et al. 13 citations
Ibogaine (IBO) is a psychoactive indole alkaloid that has antiaddictive properties. However, treatment with IBO may lead to neurotoxicity, since IBO and its metabolites interact persistently with many neurotransmitter systems. Here, we recorded cortical electroencephalogram (EEG) signals from rats anesthetized with isoflurane. The heart rate (HR) was monitored via electrocardiogram (EKG)...