5-HT1A receptor activation is necessary for 5-MeODMT-dependent potentiation of feeding inhibition.
Pharmacology, biochemistry, and behavior September 1, 2009 Vikas Duvvuri, Victoria B Risbrough, Walter H. Kaye et al. 7 citations
We propose a translational approach to the study of anorexia nervosa (AN) based on our human subject studies where there are characteristic elevations in 5-HT(1A) receptor binding, associated harm avoidance behaviors, reduced impulsivity, and comorbid anxiety disorders. Towards this goal, the hyponeophagia assay was implemented whereby food-deprived mice show increased latency to begin feeding...