With very few treatments available, post-comatose disorders of consciousness (DoC) pose one of the hardest challenges in modern neurology. Following promising clinical trial results in psychiatry, and a deepening understanding of their brain mechanisms, psychedelics have been suggested as a novel therapeutic drug for DoC patients, given that they increase the entropy or complexity of...
Current spinal cord injury treatments primarily manage symptoms rather than promote neurological recovery. Psilocybin enhances neuroplasticity through 5-HT2A agonism and brain-derived neurotrophic factor upregulation, suggesting therapeutic potential for spinal cord injury rehabilitation. We conducted semi-structured interviews with three individuals who had incomplete spinal cord injuries...