Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2).
The International Journal of Neuropsychopharmacology August 1, 2010 Nicolas Tournier, Lucie Chevillard, Bruno Mégarbane et al. 122 citations
Drug interaction with P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) may influence its tissue disposition including blood-brain barrier transport and result in potent drug-drug interactions. The limited data obtained using in-vitro models indicate that methadone, buprenorphine, and cannabinoids may interact with human P-gp; but almost nothing is known about drugs of abuse and...
DOI: 10.1017/S1461145709990848 (opens in new tab)
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Ibogaine
THC
Drug transport
Drug movement
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