Effect of Iboga alkaloids on µ-opioid receptor-coupled G protein activation.
PLoS One 2013 Tamara Antonio, Steven R Childers, Richard B Rothman et al. 36 citations
The iboga alkaloids are a class of small molecules defined structurally on the basis of a common ibogamine skeleton, some of which modify opioid withdrawal and drug self-administration in humans and preclinical models. These compounds may represent an innovative approach to neurobiological investigation and development of addiction pharmacotherapy. In particular, the use of the prototypic iboga...