Francesco Angelucci

2 papers in the library · publishing 2010-2025

Papers

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Functional and structural characterization of the human indolethylamine N-methyltransferase through fluorometric, thermal and computational docking analyses.

Biology direct April 10, 2025 Matteo Ardini, Francesco Angelucci, Francesca Rea et al.

The "psychedelic renaissance" is sparking growing interest in clinical research, along with a rise in clinical trials. Substances such as 3,4-methylenedioxymethamphetamine (MDMA), psilocybin and N,N-dimethyltryptamine (DMT) are involved. The focus of this paper is on indolethylamine N-methyltransferase (INMT), a crucial enzyme in the biosynthesis of key compounds, including DMT, which meets...

DOI: 10.1186/s13062-025-00632-z Full text DMT Dimethyltryptamine Indolethylamine n-methyltransferase assay Quinoline +5

Ecstasy (MDMA)-addicted subjects show increased serum levels of brain-derived neurotrophic factor, independently from a rise of drug-induced psychotic symptoms.

Addiction Biology July 2010 Francesco Angelucci, Valerio Ricci, Giovanni Martinotti et al.

The recreational drug 'ecstasy'[3,4-methylenedioxymethamphetamine (MDMA)] exerts a potent action on central serotonergic and dopaminergic neurons. These neurons utilize neurotrophins for their survival and function. In order to explore MDMA effects on neurotrophins, we measured by enzyme-linked immunosorbent assay the serum levels of brain-derived neurotrophic factor (BDNF) and nerve growth...

DOI: 10.1111/j.1369-1600.2010.00221.x Full text