Barbora Čechová

Psilocybin has a narrow therapeutic window as an antidepressant treatment.

Progress in Neuro-Psychopharmacology and Biological Psychiatry April 2, 2025 Lenka Seillier, Barbora Čechová, Alexandre Seillier et al. 3 citations

Psilocybin, a naturally occurring psychedelic compound in magic mushrooms, shows promise as a novel intervention with a single administration inducing rapid and long-lasting antidepressant effects. However, there are limited studies on the optimal dosing required for the beneficial effects of psilocybin given its side effects. To address this gap, we investigated in Wistar rats whether a single...