Stability-Guided Formulation of a Light-Sensitive D-LSD Capsule for Clinical Investigation.
Pharmaceutics June 11, 2025 Bernard Do, Luc Mallet, Maxime Annereau et al.
Background/Objectives: D-lysergic acid diethylamide (D-LSD) is under investigation as a potential therapeutic strategy for alcohol use disorder (AUD). However, the extreme light sensitivity of D-LSD presents a significant challenge in developing suitable pharmaceutical forms, particularly for clinical trial settings. This study proposes a liquid-filled capsule formulation designed to provide...