Ibogan, Aspidosperman, Vincamine, and Bisindole Alkaloids from a Malayan Tabernaemontana corymbosa: Iboga Alkaloids with C-20α Substitution.
Journal of Natural Products April 14, 2016 Choy-Eng Nge, Kam-Weng Chong, Noel F Thomas et al.
Ten new indole alkaloids (1-10) comprising five ibogan, two aspidosperman, one vincamine, and two bisindole alkaloids, in addition to 32 known alkaloids, were isolated from the stem-bark extract of a Malayan Tabernaemontana corymbosa. The structures of these alkaloids were determined based on analysis of the NMR and MS data and, in five instances (1, 3, 5, 6, 8), confirmed by X-ray diffraction...
DOI: 10.1021/acs.jnatprod.6b00129 (opens in new tab)
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Ibogaine
Kb cells
Humans
Tabernaemontana
+11