Randomized controlled trial of acute ketamine versus midazolam for recurrence of suicidality in adolescents (TASK): Rationale, design, and baseline characteristics.
Contemporary Clinical Trials October 8, 2026 Madhukar H. Trivedi, Cherise R Chin Fatt, Emine Rabia Ayvaci et al.
Suicide is one of the leading causes of death among adolescents in the United States. The 'Acute Course of Ketamine Versus Midazolam for Recurrence of Suicidality in Adolescents' (TASK), a double-blind, randomized, controlled trial, was designed to examine the signal for efficacy of ketamine, compared to midazolam (active control), in reducing 1) repeat suicidal events, 2) implicit cognition,...
DOI: 10.1016/j.cct.2026.108498 (opens in new tab)
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Adolescents
Intravenous ketamine
Randomized controlled trial
Suicidality
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